abstract：:The acute effects of 2-deoxy-D-glucose (2-DG)-induced glucoprivic feeding on the anorectic drug recognition site and Na+K(+)-ATPase in the brain were examined in adult rats and in lean and genetically obese mice. The marked hyperglycemia and the induction of feeding caused by the administration of 2-DG to satiated rat...

journal_title：Brain research bulletin

authors： Angel I,Hauger RL,Giblin BA,Paul SM

更新日期：1992-02-01 00:00:00

abstract：:This study analyzed the projection neurons of the anterior subdivision of the rat basolateral amygdaloid nucleus (BLa) by correlating the morphology of Golgi-stained neurons with the morphology of neurons that were retrogradely labeled by injections into the main terminal fields of BLa. In each animal multiple injecti...

journal_title：Brain research bulletin

authors： McDonald AJ

更新日期：1992-02-01 00:00:00

abstract：:The effects of intracerebroventricular (ICV) injection of neuropeptide Y (NPY) on parameters of dopamine (DA), glutamate (Glu) and gamma-aminobutyric acid (GABA) activities were investigated in the rat striatum. NPY (1.17-4.70 nmol) induced a dose-dependent increase in the striatal endogenous DA release monitored in f...

journal_title：Brain research bulletin

authors： Kerkerian-Le Goff L,Forni C,Samuel D,Bloc A,Dusticier N,Nieoullon A

更新日期：1992-02-01 00:00:00

abstract：:The effect of the intracerebroventricular (ICV) administration of pertussis toxin on penile erection and yawning induced by apomorphine and oxytocin was studied in male rats. Pertussis toxin (2 micrograms ICV) prevented the above behavioral responses to apomorphine (80 micrograms/kg SC) and oxytocin (30 ng ICV) on day...

journal_title：Brain research bulletin

authors： Stancampiano R,Melis MR,Argiolas A

更新日期：1992-02-01 00:00:00

abstract：:In order to examine the effect of chronic neuroleptics on spinal dopaminergic system, rats were treated with haloperidol (0.5 mg/kg IP) for 21 days and the monosynaptic mass reflex (MMR) as well as dopamine (DA) metabolism were investigated. MMR, recorded from ventral root L6 following supramaximal stimulation to ipsi...

journal_title：Brain research bulletin

authors： Maitra KK,Seth P,Mohanakumar KP,Ganguly DK

更新日期：1992-01-01 00:00:00

abstract：:Evidence concerning the presence or absence of common neuronglia lineages in the postnatal mammalian central nervous system is still a matter of speculation. We address this problem using optic nerve explants, which show an extremely long survival in culture. Morphological, immunocytochemical and immunochemical method...

journal_title：Brain research bulletin

authors： Omlin FX,Riederer BM

更新日期：1992-01-01 00:00:00

abstract：:For further characterization of the olfactory bulb's role in the medication of chronobiological phenomena, we examined basal cyclic- 3',5'-adenosine monophosphate (cAMP) levels in the suprachiasmatic nuclei (SCN) and lateral hippocampus (LHIP) following bilateral olfactory bulbectomy (OBX) to assess the effects of olf...

journal_title：Brain research bulletin

authors： Vagell ME,McGinnis MY,Possidente BP,Narasimhan VN,Lumia AR

更新日期：1991-12-01 00:00:00

abstract：:beta-Amyloid and related peptides are components of the neurofibrillary tangles found in the brains of patients with Alzheimer's disease and have been suggested to be directly involved in the pathophysiology of that condition. It is unclear whether the amyloid deposited in the brain arises from the peripheral circulat...

journal_title：Brain research bulletin

authors： Banks WA,Kastin AJ,Barrera CM,Maness LM

更新日期：1991-12-01 00:00:00

abstract：:A method is described for the isolation and culture of neurons in the adult mammalian brain. The cell could be maintained in primary culture for more than several weeks. Whereas the neurons freshly dissociated from the adult brain did not respond to any of the neurotransmitter substances applied, the neurons regained ...

journal_title：Brain research bulletin

authors： Ogata N,Tatebayashi H

更新日期：1991-11-01 00:00:00

abstract：:The distribution of calcitonin gene-related peptide (CGRP)-like immunoreactive (LI) nerve cells and terminals (BST) was studied in the rat. Only the fusiform nucleus was found to consistently contain CGRP-LI neurons. The CRGP-LI terminals had a wide distribution in the BST, being most numerous in the oval and the fusi...

journal_title：Brain research bulletin

authors： Ju G

更新日期：1991-11-01 00:00:00

abstract：:Unilateral injections of 6-hydroxydopamine (6-OHDA) cause significant bilateral increases in striatal proenkephalin (PEK) mRNA in rat brain. We have tested the possibility that implantation of fetal mesencephalic cells can normalize these changes. Two types of grafts were used: 1) embryonic day-15 mesencephalic cells ...

journal_title：Brain research bulletin

authors： Cadet JL,Zhu SM,Angulo JA

更新日期：1991-11-01 00:00:00

abstract：:The present study investigated whether the raphe neurons which give rise to the transient serotonergic fibers in the visual cortex of neonatal rats persist or disappear as the rats mature. Three experiments were performed employing the WGA-apoHRP-Au retrograde transport technique in conjunction with 5-HT or WGA-HRP im...

journal_title：Brain research bulletin

authors： Koh T,Nakazawa M,Kani K,Maeda T

更新日期：1991-11-01 00:00:00

abstract：:Our previous results showed that neurochemical destruction of the amygdaloid terminal field of the mesolimbic dopaminergic system caused disturbances in body weight regulation and feeding. In the present experiments, it was studied whether 6-hydroxydopamine (6-OHDA)-induced bilateral lesions of the mesolimbic dopamine...

journal_title：Brain research bulletin

authors： Lénárd L,Karádi Z,Jandó G,Yoshimatsu H,Hajnal A,Sándor P,Oomura Y

更新日期：1991-09-01 00:00:00

abstract：:Three sets of experiments have been conducted that suggest that adrenal glucocorticoids play a role in the long-term control of intake and in dietary preferences. First, obesity is dependent upon glucocorticoid-modulated metabolic pathways. Surgical or pharmacological manipulations in obese animals that eliminate or d...

journal_title：Brain research bulletin

authors： Castonguay TW

更新日期：1991-09-01 00:00:00

abstract：:Long chain fatty acids (FA) and 2-monoacylglycerols (MG) are produced by lipoprotein lipase (LPL) from plasma triacylglycerols (TG) in capillaries of adipose tissue and transported to adipocytes for TG synthesis. It is widely proposed FA may be transported in cells by FA-binding protein. Mode of transport of MG has re...

journal_title：Brain research bulletin

authors： Scow RO,Blanchette-Mackie EJ

更新日期：1991-09-01 00:00:00

abstract：:The biochemical balance between right- and left-ascending DA systems is an essential factor to regulate behavioral lateralization. However, there is no electrophysiological evidence for the regulation of interhemispheric DA systems. In the present paper we report electrophysiological evidence supporting the hypothesis...

journal_title：Brain research bulletin

authors： Castellano MA,Rodriguez Diaz M

更新日期：1991-08-01 00:00:00

abstract：:Neonatal rats, when spinalized on the fourteenth postnatal day, showed minimal recovery of function in their hindlimbs. Bridging the cut spinal cord with E16 fetal spinal cord tissue did not improve functional recovery. Bridging, plus treatment with GM1 ganglioside, caused a significant (p less than 0.05) improvement ...

journal_title：Brain research bulletin

authors： Commissiong JW,Sauve Y,Csonka K,Karoum F,Toffano G

更新日期：1991-07-01 00:00:00

abstract：:The use of a new and very sensitive immunohistochemical method, combined with intracerebral injections of colchicine, has allowed us to show that a number of nerve cell bodies immunoreactive for Met-enkephalin are present in several mesencephalic nuclei of the rat, including the different subdivisions of the substanti...

journal_title：Brain research bulletin

authors： Vankova M,Arluison M,Boyer PA,Bourgoin S,Quignon M

更新日期：1991-07-01 00:00:00

abstract：:Sleep EEG in the sigma and delta frequency bands was subjected to spectral analysis in 8 normal young adults. In each subject, power density of sigma and delta oscillated reciprocally during NREM sleep, confirming an observation made initially with period/amplitude analysis. In REM sleep, power density for both freque...

journal_title：Brain research bulletin

authors： Uchida S,Maloney T,March JD,Azari R,Feinberg I

更新日期：1991-07-01 00:00:00

abstract：:Reports from both this laboratory and others indicate that prenatal exposure of rats to cocaine can produce alterations in development, activity and responses to environmental stimuli. In order to determine a biochemical basis for these effects, radioligand receptor-binding assays for different monoaminergic receptors...

journal_title：Brain research bulletin

authors： Henderson MG,McConnaughey MM,McMillen BA

更新日期：1991-06-01 00:00:00

abstract：:The volume and neuron number of the sexually dimorphic accessory olfactory bulb and locus coeruleus are altered by early postnatal exposure (from the day of birth to postnatal day 16) to diazepam. After diazepam treatment, both volume and neuron number were decreased in the male accessory olfactory bulb and in the fem...

journal_title：Brain research bulletin

authors： Segovia S,Pérez-Laso C,Rodríguez-Zafra M,Calés JM,Del Abril A,De Blas MR,Collado P,Valencia A,Guillamón A

更新日期：1991-06-01 00:00:00

abstract：:Prior results (37) showed that morphine pretreatment reduces the escape response of the crab Chasmagnathus to a shadow passing overhead and prevents the acquisition of a long-term habituation. These results were explained by a reduction in the danger signalled by the stimulus, and to test this hypothesis methods other...

journal_title：Brain research bulletin

authors： Tomsic D,Maldonado H,Rakitin A

更新日期：1991-05-01 00:00:00

abstract：:Simultaneous blood and cerebrospinal fluid (CSF) samples were taken from conscious sheep before, during and after parturition. Concentrations of plasma and CSF oxytocin were significantly elevated during contractions and particularly at birth. Mean prepartum CSF concentrations of oxytocin were around 55% of those foun...

journal_title：Brain research bulletin

authors： Kendrick KM,Keverne EB,Hinton MR,Goode JA

更新日期：1991-05-01 00:00:00

abstract：:Most of the lateral hypothalamic neurons responding to moderate changes in blood glucose fail to be affected by direct glucose applications. Therefore their sensitivity to glycemic level must be mediated by an indirect mechanism. In order to test whether adrenergic afferents might be involved, the activity of lateral ...

journal_title：Brain research bulletin

authors： Orsini JC,Wiser AK,Himmi T,Boyer A,Perrin J

更新日期：1991-04-01 00:00:00

abstract：:Hoe 065 is a compound structurally related to the angiotensin converting enzyme inhibitors and capable of increasing central cholinergic activity. The effects of this compound were studied on alcohol intake and on the reduction in alcohol intake produced by abutapril, an angiotensin converting enzyme inhibitor. Hoe 06...

journal_title：Brain research bulletin

authors： Grupp LA,Chow SY

更新日期：1991-04-01 00:00:00

abstract：:The effect of bilateral colchicine lesions of the nucleus basalis magnocellularis (NBM) on agonist-stimulated phosphoinositide (PI) hydrolysis was examined in cortical slices 1, 3, or 14 months after surgery. Colchicine lesions resulted in a loss of acetylcholinesterase staining in the cortex which recovered to contro...

journal_title：Brain research bulletin

authors： Mundy WR,Tandon P,Barone S Jr,Tilson HA

更新日期：1991-04-01 00:00:00

abstract：:This study was performed to elucidate the mechanism by which adenosine triphosphate (ATP) encapsulated into liposomes was able to protect against experimental brain ischemia in the rat. After intracarotidal administration of liposomally entrapped ATP, the ATP blood level increased dramatically whereas no change was ob...

journal_title：Brain research bulletin

authors： Chapat S,Frey V,Claperon N,Bouchaud C,Puisieux F,Couvreur P,Rossignol P,Delattre J

更新日期：1991-03-01 00:00:00

abstract：:The electroencephalographic (EEG) activity of the hippocampus was examined in adult freely moving rats that had had all of the neocortex, including the cingulate cortex and cingulum, removed at birth. Both the cholinergic and serotonergic forms of rhythmical slow activity (RSA or theta) were present in the dorsal hipp...

journal_title：Brain research bulletin

authors： Whishaw IQ,Dyck R,Kolb B

更新日期：1991-03-01 00:00:00

abstract：:We studied the ontogeny of muscarinic depression in the developing rat visual cortex using carbachol (a nonhydrolyzable cholinergic agonist) application to neocortical slices obtained from four postnatal age groups: 9-10 days, 15 days, 30-40 days and 18 months. Carbachol suppressed the evoked synaptic response of laye...

journal_title：Brain research bulletin

authors： Vaknin G,Teyler TJ

更新日期：1991-02-01 00:00:00

abstract：:Functional interactions between the basal ganglia and the perioral area were analyzed by means of electrical brain stimulation in the rat. The first experiment showed that unilateral stimulation of the substantia nigra sensitized the contralateral perioral area for a biting reflex upon its tactile stimulation. This bi...

journal_title：Brain research bulletin

authors： Schwarting RK,Elstermeier F,Francke W,Huston JP

更新日期：1991-02-01 00:00:00

abstract：:Several lines of evidence have established that performance during the initial steps of acquisition on a shuttle-box avoidance task is an anxiety-mediated behavior (i.e., the differences between strains selectivity bred for emotionality; the effects of postnatal handling; the course of the corticosterone response and ...

journal_title：Brain research bulletin

authors： Fernández-Teruel A,Escorihuela RM,Núñez JF,Zapata A,Boix F,Salazar W,Tobeña A

更新日期：1991-01-01 00:00:00

abstract：:Body weight changes and food and water intakes were studied in CFY male and female rats after kainic acid (KA)-induced destruction of the lateral hypothalamic area (LH) or the ventromedial hypothalamic nucleus (VMH). To minimize the extent of damages, KA was iontophoretically applied by means of glass micropipettes. K...

journal_title：Brain research bulletin

authors： Lénárd L,Sándor P,Hajnal A,Jandó G,Karádi Z,Kai Y

更新日期：1991-01-01 00:00:00

abstract：:Chemical studies have demonstrated that peptides such as the encephalitogenic (EAE) peptide of myelin basic protein (MBP) and luteinizing hormone-releasing hormone (LHRH) can bind serotonin (5-hydroxytryptamine, 5-HT) in vitro. The present research was undertaken to determine whether such binding interferes with 5-HT ...

journal_title：Brain research bulletin

authors： Takeuchi Y,Root-Bernstein RS,Shih JC

更新日期：1990-12-01 00:00:00

abstract：:It is now generally recognized that interleukin-6 (IL6) is one of the cytokines that mediate the various nonspecific host defense responses to infectious pathogens. Among its now well-demonstrated effects on systemic administration are fever and acute-phase proteinemia. These effects are also activated by the cytokine...

journal_title：Brain research bulletin

authors： Blatteis CM,Quan N,Xin L,Ungar AL

更新日期：1990-12-01 00:00:00

abstract：:Although it is well established that increases in tryptophan availability can increase brain serotonin synthesis, the effect of tryptophan loads on serotonin release is not as clear. We have used in vivo microdialysis in order to monitor extracellular serotonin in the lateral hypothalamus to examine this issue. Trypto...

journal_title：Brain research bulletin

authors： Schwartz DH,Hernandez L,Hoebel BG

更新日期：1990-12-01 00:00:00

abstract：:The effects of electrical stimulation of the "mesencephalic locomotor region" and adjacent dorsolateral tegmentum were assessed and compared in the same rats in freely moving conditions or when lightly anesthetized and suspended over a moving treadmill. In freely moving conditions, electrical brain stimulation (EBS) o...

journal_title：Brain research bulletin

authors： Depoortere R,Di Scala G,Sandner G

更新日期：1990-11-01 00:00:00

abstract：:A microdialysis probe, implanted in the posterior hypothalamus (PH) was used to examine changes of extracellular norepinephrine (NE) in freely moving rats from which mean arterial pressure (mAP) and heart rate (HR) were continuously monitored. Artificial cerebrospinal fluid (aCSF) was pumped through the probe and 10-m...

journal_title：Brain research bulletin

authors： Nakata T,Berard W,Kogosov E,Alexander N

更新日期：1990-10-01 00:00:00

abstract：:After placing bilateral electrolytic lesions in the fasciculus retroflexus (FR) of the rat, the endogenous content of serotonin, glutamate and gamma-aminobutyrate (GABA) as well as choline acetyltransferase activity (ChAT) were measured in the interpeduncular nucleus (IPN) at the 7th, 28th and 120th survival days. Con...

journal_title：Brain research bulletin

authors： Takishita N,Kubo H,Mitani A,Nakamura Y,Masuda S,Iwahashi K,Kataoka K

更新日期：1990-10-01 00:00:00

abstract：:Bilateral inferior olive lesions, produced by systemic administration of the neurotoxin 3-acetylpyridine (3AP) produce a proconvulsant state specific for strychnine-induced seizures and myoclonus. We have proposed that these phenomena are mediated through increased excitation of cerebellar Purkinje cells, through acti...

journal_title：Brain research bulletin

authors： Anderson MC,Chung EY,Van Woert MH

更新日期：1990-10-01 00:00:00

abstract：:A modified synaptosomal superfusion apparatus is described which uses less than 10 micrograms of tissue per replicate sample and facilitates the routine separation of 3H-DA, 3H-DOPAC, and 3H-HVA. A flow rate of 1.5 ml/min allows superfusion without the use of reuptake or monoamine oxidase inhibitors. Superfusate sampl...

journal_title：Brain research bulletin

authors： Petrie EC,Lombrozo L,Csernansky JG

更新日期：1990-09-01 00:00:00